HitPredict

Interactor 1: UB2E3 (Q969T4)
Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3)
Gene: UBE2E3

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	19549727, 32814053
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Hs			1 154
+	Hs
		1297380 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		1377465 UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		207566 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		RNF13_HUMAN (77-146): 1.55e-26: 104: 33.80
+	Hs
		1282368 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		RN115_HUMAN (10-154): 2e-26: 102: 19.08
+	Hs
		1204805 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		1297382 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		RN115_HUMAN (10-154): 2e-26: 102: 19.08
+	Hs
		1282364 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		RN150_HUMAN (57-146): 3.61e-24: 98.4: 26.67
+	Hs
		1282346 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		RN167_HUMAN (77-143): 4.96e-21: 89.1: 36.77
+	Hs
		1297371 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		207572 UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01		RNF13_HUMAN (77-146): 1.55e-26: 104: 33.80
+	Hs
		207553 UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07		RNF13_HUMAN (77-146): 1.55e-26: 104: 33.80
+	Hs
		1377467 UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01		RN115_HUMAN (10-154): 2e-26: 102: 19.08
+	Hs
		1204871 UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		919789 UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07		RN149_HUMAN (54-147): 1.09e-25: 102: 34.04
+	Hs
		919772 UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		1356934 UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01		RN150_HUMAN (57-146): 3.61e-24: 98.4: 26.67
+	Hs
		919766 UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07		SYVN1_HUMAN (72-152): 3.43e-24: 99.2: 28.40
+	Hs
		1346940 UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		1332598 UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01		RN167_HUMAN (77-143): 4.96e-21: 89.1: 36.77
+	Hs
		919862 UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07		RN167_HUMAN (77-143): 4.96e-21: 89.1: 36.77