HitPredict

Interactor 1: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Interactor 2: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~SET
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 127 Hs			1 1210
+	Hs
		1087341 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		918611 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		1231227 H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		1087410 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		918699 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		1282965 H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		203602 H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25		SUV91_HUMAN (861-1179): 1.67e-78: 266: 30.51
+	Hs
		862088 H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37		DAPK1_HUMAN (672-1049): 2.27e-52: 203: 17.06
+	Sp
		223810 H2B1_SCHPO (5-126): 8.55e-46: 146: 69.67		CLR4_SCHPO (924-1176): 3.8e-36: 145: 34.95
+	Hs
		1274409 H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37		ASPP1_HUMAN (755-871): 8.39e-14: 78.5: 20.00