HitPredict

Interactor 1: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Interactor 2: UBE2O (Q9C0C9)
(E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O)
Gene: UBE2O

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 127 Hs			1 1292
+	Hs
		918666 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		UBE2O_HUMAN (40-1292): 0: 1481: 100.00
+	Hs
		1231241 H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83		UBE2O_HUMAN (40-1292): 0: 1481: 100.00
+	Mm
		1145473 H2B2B_MOUSE (5-127): 1.83e-54: 168: 85.37		UBE2A_MOUSE (956-1112): 5.42e-42: 152: 26.75
+	Hs
		829009 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		UBE2A_HUMAN (956-1112): 5.42e-42: 152: 26.75
+	Hs
		707552 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		UBE2A_HUMAN (956-1112): 5.42e-42: 152: 26.75
+	Hs
		828968 H2B1D_HUMAN (1-127): 1.37e-53: 166: 85.04		UBE2A_HUMAN (956-1112): 5.42e-42: 152: 26.75
+	Hs
		828971 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		UBE2A_HUMAN (956-1112): 5.42e-42: 152: 26.75
+	Mm
		927791 H2B2B_MOUSE (5-127): 1.83e-54: 168: 85.37		UBE2B_MOUSE (956-1112): 2.98e-41: 150: 27.39
+	Hs
		927767 H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00		UBE2B_HUMAN (956-1112): 2.98e-41: 150: 27.39
+	Sc
		355730 H2B2_YEAST (4-126): 4.46e-41: 134: 69.36		UBC2_YEAST (956-1112): 4.12e-41: 151: 25.48