HitPredict

Interactor 1: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Interactor 2: CBX8 (Q9HC52)
Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1)
Gene: CBX8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21282530
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 127 Hs			1 389
+	Hs
		1087415 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CBX8_HUMAN (1-389): 5.01e-104: 314: 100.00
+	Hs
		241642 H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25		CBX8_HUMAN (1-389): 5.01e-104: 314: 100.00
+	Hs
		707753 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		CBX8_HUMAN (1-389): 5.01e-104: 314: 100.00
+	Hs
		1087494 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CDYL_HUMAN (2-312): 1.24e-66: 223: 14.65
+	Hs
		316041 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CBX6_HUMAN (1-386): 1.08e-65: 216: 33.26
+	Hs
		315974 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		CBX6_HUMAN (1-386): 1.08e-65: 216: 33.26
+	Hs
		123255 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CBX4_HUMAN (1-349): 3.84e-62: 210: 21.93
+	Hs
		123191 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		CBX4_HUMAN (1-349): 3.84e-62: 210: 21.93
+	Hs
		1087361 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		MPP8_HUMAN (6-356): 2.27e-52: 188: 18.85
+	Hs
		1059155 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CBX2_HUMAN (2-348): 3.75e-46: 167: 22.03
+	Hs
		707633 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		CBX2_HUMAN (2-348): 3.75e-46: 167: 22.03
+	Hs
		203602 H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25		SUV91_HUMAN (11-102): 9.92e-27: 112: 25.25
+	Hs
		1027018 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CBX3_HUMAN (9-144): 1.3e-26: 106: 25.74
+	Hs
		420833 H2B1J_HUMAN (1-127): 4.39e-54: 167: 85.04		CBX3_HUMAN (9-144): 1.3e-26: 106: 25.74
+	Hs
		241519 H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25		CBX3_HUMAN (9-144): 1.3e-26: 106: 25.74
+	Hs
		800398 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CBX5_HUMAN (11-144): 1.06e-25: 104: 25.00
+	Hs
		241469 H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25		CBX5_HUMAN (11-144): 1.06e-25: 104: 25.00
+	Hs
		420825 H2B1J_HUMAN (1-127): 4.39e-54: 167: 85.04		CBX1_HUMAN (17-122): 3.63e-23: 97.5: 28.97
+	Hs
		949797 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CBX1_HUMAN (17-122): 3.63e-23: 97.5: 28.97
+	Hs
		707585 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		CBX1_HUMAN (17-122): 3.63e-23: 97.5: 28.97