HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	36950384
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 2581
+	Hs
		1336297 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	Hs
		1336317 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	Hs
		516702 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	Hs
		128156 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018725 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1059908 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Dm
		332909 Q9VZ69_DROME (172-572): 2.54e-79: 262: 41.15		CHDM_DROME (439-2066): 0: 997: 22.94
+	Hs
		1018494 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018628 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018495 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018777 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018458 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		516483 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1059629 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1031332 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		516522 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		CHD4_HUMAN (500-2065): 0: 981: 23.88