HitPredict

Interactor 1: FERM2 (Q96AC1)
Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1)
Gene: FERMT2

Interactor 2: FERM1 (Q9BQL6)
Fermitin family homolog 1 (Kindlerin) (Kindlin syndrome protein) (Kindlin-1) (Unc-112-related protein 1)
Gene: FERMT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

The method score is based on:

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	FERM_M~FERM_M, PH~PH
Common GO terms	GO:0005178 - integrin binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0007155 - cell adhesion and 6 others more... GO:0007160 - cell-matrix adhesion GO:0007229 - integrin-mediated signaling pathway GO:0030054 - cell junction GO:0033625 - positive regulation of integrin activation GO:0051015 - actin filament binding GO:1903691 - positive regulation of wound healing, spreading of epidermal cells
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	680
Hs

1	677

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024