Interactor 1: EME1 (Q96AY2)
Crossover junction endonuclease EME1 (EC 3.1.22.-) (MMS4 homolog) (hMMS4)
Gene: EME1

Interactor 2: MUS81 (Q96NY9)
Crossover junction endonuclease MUS81 (EC 3.1.22.-)
Gene: MUS81

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 29738624, 14617801, 19596236, 19363487, 25224045, 28514442, 25319828, 27354282, 18413719, 12721304, 28575661, 33961781, 21962513, 19017809, 17289582, 12686547, 24733841
Identification Methods pull down, affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation, gal4 vp16 complementation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ERCC4~ERCC4
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006302 - double-strand break repair
and 8 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 570
Hs

1 551
+ Mm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024