HitPredict

Interactor 1: UBE2W (Q96B02)
Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (N-terminus-conjugating E2) (Ubiquitin carrier protein W) (Ubiquitin-conjugating enzyme 16) (UBC-16) (Ubiquitin-protein ligase W)
Gene: UBE2W

Interactor 2: RMD5B (Q96G75)
E3 ubiquitin-protein transferase RMND5B (EC 2.3.2.27) (Protein RMD5 homolog B)
Gene: RMND5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 151 Hs			1 393
+	Hs
		1291949 UB2D4_HUMAN (4-150): 7.3e-70: 208: 35.37		RMD5B_HUMAN (1-393): 4e-147: 424: 100.00
+	Hs
		919825 UB2D2_HUMAN (4-150): 1.14e-68: 205: 33.33		RMD5B_HUMAN (1-393): 4e-147: 424: 100.00
+	Hs
		895879 UB2D3_HUMAN (4-150): 3.12e-67: 202: 33.33		RMD5B_HUMAN (1-393): 4e-147: 424: 100.00
+	Hs
		1282327 UB2E3_HUMAN (1-150): 1.13e-65: 200: 35.33		RMD5B_HUMAN (1-393): 4e-147: 424: 100.00
+	Hs
		851869 UB2E1_HUMAN (1-150): 3.64e-64: 196: 34.00		RMD5B_HUMAN (1-393): 4e-147: 424: 100.00
+	Hs
		895826 UB2D3_HUMAN (4-150): 3.12e-67: 202: 33.33		MAEA_HUMAN (1-392): 3.27e-115: 342: 20.36
+	Zm
		35306 A0A1D6LKH6_MAIZE (1-148): 1.2e-63: 194: 30.20		A0A1D6Q353_MAIZE (102-282): 3.43e-11: 66.3: 11.33