HitPredict

Interactor 1: UBE2W (Q96B02)
Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (N-terminus-conjugating E2) (Ubiquitin carrier protein W) (Ubiquitin-conjugating enzyme 16) (UBC-16) (Ubiquitin-protein ligase W)
Gene: UBE2W

Interactor 2: RN167 (Q9H6Y7)
E3 ubiquitin-protein ligase RNF167 (EC 2.3.2.27) (RING finger protein 167)
Gene: RNF167

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.868

The method score is based on:

Property Details
Experiments 33650289, 33961781, 19690564
Identification Methods pull down, affinity chromatography technology, two hybrid, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-RING_2
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 151
Hs

1 350
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024