HitPredict

Interactor 1: UBE2W (Q96B02)
Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (N-terminus-conjugating E2) (Ubiquitin carrier protein W) (Ubiquitin-conjugating enzyme 16) (UBC-16) (Ubiquitin-protein ligase W)
Gene: UBE2W

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 21855799, 28757353, 26010904, 23696636, 32401531, 21518764, 23560854
Identification Methods enzymatic study, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains U-box~UQ_con
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 6 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 151
Hs

1 303
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024