HitPredict

Interactor 1: EXOS8 (Q96B26)
Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9)
Gene: EXOSC8

Interactor 2: EXOS5 (Q9NQT4)
Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)
Gene: EXOSC5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 25416956, 26186194, 21516116, 28514442, 34133714, 12419256, 15231747, 26496610, 32296183, 24981860, 33961781, 31515488, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNase_PH~RNase_PH, RNase_PH~RNase_PH_C, RNase_PH_C~RNase_PH_C
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 8 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 276
Hs

1 235
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Last updated: 15 Jul 2024