Interactor 1: EXOS8 (Q96B26)
Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9)
Gene: EXOSC8
Interactor 2: EXOS1 (Q9Y3B2)
Exosome complex component CSL4 (Exosome component 1)
Gene: EXOSC1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.94 | 1.00 | 0.974 |
The method score is based on:
Property | Details |
---|---|
Experiments | 26186194, 32296183, 15231747, 26496610, 28514442, 24981860, 33961781, 34133714, unassigned1304 |
Identification Methods | affinity chromatography technology, two hybrid, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | ECR1_N~RNase_PH, EXOSC1~RNase_PH, ECR1_N~RNase_PH_C |
Common GO terms | GO:0000176 - nuclear exosome (RNase complex) GO:0000177 - cytoplasmic exosome (RNase complex) GO:0000178 - exosome (RNase complex) GO:0005634 - nucleus GO:0005654 - nucleoplasm and 6 others more... |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024