Interactor 1: EXOS8 (Q96B26)
Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9)
Gene: EXOSC8

Interactor 2: EXOS1 (Q9Y3B2)
Exosome complex component CSL4 (Exosome component 1)
Gene: EXOSC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 26186194, 32296183, 15231747, 26496610, 28514442, 24981860, 33961781, 34133714, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ECR1_N~RNase_PH, EXOSC1~RNase_PH, ECR1_N~RNase_PH_C
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 276
Hs

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Last updated: 15 Jul 2024