HitPredict

Interactor 1: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Interactor 2: BACD3 (Q9H3F6)
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10)
Gene: KCTD10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 19531213
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 665 Hs			1 313
+	Hs
		1252625 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		SHKB1_HUMAN (22-134): 1.86e-36: 140: 32.17
+	Hs
		1330034 ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30		BACD3_HUMAN (1-313): 1.76e-133: 383: 100.00
+	Hs
		924556 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		BACD2_HUMAN (4-313): 9.13e-120: 348: 70.06
+	Hs
		924719 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		SHKB1_HUMAN (22-134): 1.86e-36: 140: 32.17
+	Hs
		209114 NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77		KCD17_HUMAN (32-156): 3.05e-39: 142: 32.82