HitPredict

Interactor 1: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Interactor 2: ASAP1 (Q9ULH1)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)
Gene: ASAP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	1.00	0.962

Property	Details
Experiments	28514442, 31980649, 33961781, 19531213, 17255943, 15090612, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_9, PH~SH3_9, SH3_9~SH3_9
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 665 Hs			1 1129
+	Hs
		1356881 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		195796 Q5JPT6_HUMAN (1-665): 8.63e-127: 391: 100.00		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		195804 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		557823 NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		924943 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		195783 NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		195791 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		195795 ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		1285175 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		ARAP1_HUMAN (368-620): 3.83e-58: 222: 24.90
+	Hs
		557696 NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81		ACAP1_HUMAN (45-690): 2.77e-153: 477: 21.01
+	Hs
		1262750 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		ARAP3_HUMAN (368-605): 4.78e-56: 215: 27.46
+	Hs
		924582 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		ACAP1_HUMAN (45-690): 2.77e-153: 477: 21.01
+	Hs
		1262768 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		ARAP3_HUMAN (368-605): 4.78e-56: 215: 27.46
+	Hs
		1136563 SPD2A_HUMAN (1-631): 1.05e-46: 180: 14.72		AGAP1_HUMAN (361-662): 1.75e-62: 231: 28.30
+	Dm
		1279243 Q9VIN1_DROME (2-656): 1.03e-49: 186: 16.50		GIT_DROME (452-692): 2.89e-58: 217: 24.41
+	Hs
		557775 NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81		ARAP1_HUMAN (368-620): 3.83e-58: 222: 24.90
+	Hs
		924798 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		ARAP1_HUMAN (368-620): 3.83e-58: 222: 24.90
+	Hs
		557688 NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81		GIT2_HUMAN (446-1074): 4.12e-57: 213: 16.98
+	Dm
		1368053 Q9VIN1_DROME (2-656): 1.03e-49: 186: 16.50		RHGF_DROME (680-1127): 1.73e-15: 83.7: 11.37
+	Hs
		1078880 ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21