HitPredict

Interactor 1: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	33961781, 19531213
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 665 Hs			1 2752
+	Hs
		821003 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		807680 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		924473 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		MAP1A_HUMAN (170-2540): 2.1e-44: 181: 9.15
+	Hs
		557777 NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		924808 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		820875 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		557660 NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		924484 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		924760 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		PRG4_HUMAN (2419-2752): 3.04e-09: 65: 11.64
+	Hs
		209006 NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65