HitPredict

Interactor 1: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Interactor 2: SHLB1 (Q9Y371)
Endophilin-B1 (Bax-interacting factor 1) (Bif-1) (SH3 domain-containing GRB2-like protein B1)
Gene: SH3GLB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11894096
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SH3_9~SH3_9
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 665 Hs			1 365
+	Hs
		1285199 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		SHLB2_HUMAN (4-365): 1.68e-73: 235: 55.95
+	Hs
		1285181 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		SH3G3_HUMAN (13-364): 7.3e-74: 234: 24.37
+	Hs
		1285180 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		SH3G2_HUMAN (13-364): 5.69e-72: 229: 25.49
+	Hs
		1285179 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		SH3G1_HUMAN (13-364): 7.6e-69: 222: 24.87
+	Mm
		1143925 SH3K1_MOUSE (1-665): 4.53e-118: 370: 87.59		SH3G2_MOUSE (13-364): 9.44e-72: 229: 25.77
+	Hs
		1089305 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		RHG44_HUMAN (18-264): 2.02e-50: 182: 18.15
+	Hs
		1307444 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		SH3G2_HUMAN (13-364): 5.69e-72: 229: 25.49
+	Hs
		1148382 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		RHG17_HUMAN (16-263): 2.22e-39: 150: 16.28
+	Hs
		1089312 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		RHG44_HUMAN (18-264): 2.02e-50: 182: 18.15
+	Hs
		1052363 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		SRC8_HUMAN (28-363): 6.84e-40: 150: 16.29
+	Hs
		1148393 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		RHG17_HUMAN (16-263): 2.22e-39: 150: 16.28
+	Hs
		1126372 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		SH319_HUMAN (287-364): 1.16e-12: 71.3: 32.91
+	Hs
		1285205 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		ITSN2_HUMAN (299-362): 7.68e-09: 59.5: 23.44
+	Hs
		1052222 SPD2A_HUMAN (1-631): 1.05e-46: 180: 14.72		SRC8_HUMAN (28-363): 6.84e-40: 150: 16.29
+	Rn
		71363 B2RZ33_RAT (104-421): 1.29e-32: 131: 15.93		SRC8_RAT (31-363): 2.95e-41: 153: 16.47
+	Hs
		924570 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		SRC8_HUMAN (28-363): 6.84e-40: 150: 16.29
+	Hs
		924555 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		SPTN1_HUMAN (8-365): 6.77e-38: 147: 12.74
+	Hs
		1191849 SH3R2_HUMAN (1-597): 1.19e-43: 169: 16.35		SH3R1_HUMAN (273-365): 7.1e-09: 59.5: 19.59
+	Mm
		1141153 GRB2_MOUSE (2-158): 6.83e-33: 128: 19.91		SH3K1_MOUSE (287-364): 2.01e-12: 70.6: 21.80
+	Mm
		1141129 GRB2_MOUSE (2-158): 6.83e-33: 128: 19.91		VAV2_MOUSE (220-362): 4.94e-12: 69.4: 24.32