HitPredict

Interactor 1: PF21A (Q96BD5)
PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)
Gene: PHF21A

Interactor 2: ZMYD8 (Q9ULU4)
MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8)
Gene: ZMYND8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31753913, 34709266
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD, PHD~PHD
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 680 Hs			1 1186
+	Hs
		782398 KDM5C_HUMAN (169-655): 3.08e-60: 221: 15.75		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		666553 KDM5A_HUMAN (211-656): 1.39e-54: 204: 16.12		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		170511 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Mm
		1145015 TRI33_MOUSE (2-648): 5.71e-84: 289: 15.96		TIF1A_MOUSE (38-252): 7.15e-49: 191: 27.39
+	Hs
		987484 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		MTG8_HUMAN (948-1118): 4.47e-49: 187: 20.57
+	Hs
		600203 PF21A_HUMAN (1-680): 2.54e-112: 355: 100.00		TAF1_HUMAN (14-254): 1.28e-24: 114: 20.57
+	Hs
		170170 TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Hs
		203475 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		MTG8R_HUMAN (949-1120): 2.94e-44: 172: 20.46
+	Hs
		1357682 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		TRI33_HUMAN (12-288): 1.97e-42: 171: 22.09
+	Mm
		1145011 TIF1A_MOUSE (2-647): 3.9e-78: 271: 13.80		TIF1A_MOUSE (38-252): 7.15e-49: 191: 27.39
+	Mm
		1266177 TRI66_MOUSE (2-647): 1.24e-71: 255: 16.37		TRI66_MOUSE (20-306): 4.69e-53: 206: 20.72
+	Hs
		254019 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		MTG16_HUMAN (948-1103): 2.32e-42: 167: 24.85
+	Hs
		1355775 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		BAZ2A_HUMAN (82-251): 2.51e-37: 155: 18.50
+	Hs
		164439 TRI66_HUMAN (2-647): 2.96e-69: 248: 14.35		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		1017367 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		782401 KDM5C_HUMAN (169-655): 3.08e-60: 221: 15.75		TRI33_HUMAN (12-288): 1.97e-42: 171: 22.09
+	Hs
		1199218 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		782356 KDM5C_HUMAN (169-655): 3.08e-60: 221: 15.75		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57