HitPredict

Interactor 1: Q96BE0 (Q96BE0)
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)
Gene: Q96BE0

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	25036637
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	ANAPC3~HSP70
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 269 Hs			1 303
+	Hs
		714095 HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		504954 HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Mm
		926173 HSP7C_MOUSE (1-269): 1.33e-130: 385: 99.63		CHIP_MOUSE (1-303): 1.23e-67: 214: 97.37
+	Mm
		571871 HS71B_MOUSE (1-269): 4.29e-130: 384: 77.70		CHIP_MOUSE (1-303): 1.23e-67: 214: 97.37
+	Dm
		505122 HSP7D_DROME (1-235): 1.12e-128: 380: 82.55		Q9XYW6_DROME (28-303): 2.4e-57: 187: 57.25
+	Ce
		105586 HSP1_CAEEL (1-269): 1.5e-134: 395: 79.93		G5ECY6_CAEEL (26-301): 5.16e-47: 160: 38.77
+	At
		1338010 HS704_ARATH (1-269): 3.47e-132: 389: 70.26		CHIP_ARATH (17-300): 4.28e-49: 166: 32.17
+	Hs
		297027 HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00		TOM70_HUMAN (4-212): 8.69e-40: 148: 22.47
+	Dm
		505095 HSP7D_DROME (1-235): 1.12e-128: 380: 82.55		Q9VJD4_DROME (19-202): 9.28e-42: 148: 25.54
+	Mm
		926131 HSP7C_MOUSE (1-269): 1.33e-130: 385: 99.63		PPP5_MOUSE (1-259): 7.23e-36: 136: 20.91
+	Hs
		503738 HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	At
		99225 HS701_ARATH (1-269): 7.3e-134: 394: 69.89		OE64M_ARATH (4-137): 1.67e-31: 125: 25.37
+	At
		612321 HS701_ARATH (1-269): 7.3e-134: 394: 69.89		OE64C_ARATH (22-129): 4.48e-31: 123: 32.41
+	Hs
		213468 HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Mm
		926144 HSP7C_MOUSE (1-269): 1.33e-130: 385: 99.63		SGTA_MOUSE (4-140): 2.54e-32: 123: 28.47
+	Mm
		1143060 HS71A_MOUSE (1-269): 1.94e-129: 382: 76.95		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	At
		1338008 HS704_ARATH (1-269): 3.47e-132: 389: 70.26		HSOP1_ARATH (32-275): 6.03e-19: 88.9: 16.47
+	Dm
		505103 HSP7D_DROME (1-235): 1.12e-128: 380: 82.55		Q9VPN5_DROME (26-202): 1.32e-15: 78.6: 17.30
+	Hs
		713982 HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58		TOM34_HUMAN (26-117): 9.37e-11: 63.5: 35.87
+	Ce
		183700 HSP1_CAEEL (1-269): 1.5e-134: 395: 79.93		STIP1_CAEEL (26-124): 4.72e-10: 61.6: 36.36