HitPredict

Interactor 1: RNF25 (Q96BH1)
E3 ubiquitin-protein ligase RNF25 (EC 2.3.2.27) (RING finger protein 25) (RING finger protein AO7)
Gene: RNF25

Interactor 2: UB2E2 (Q96LR5)
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Gene: UBE2E2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.875

The method score is based on:

Property Details
Experiments 28514442, 33961781, 19549727
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RWD~UQ_con, UQ_con~zf-RING_2
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 459
Hs

1 201
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ At
+ At
+ Zm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024