Interactor 1: DCPS (Q96C86)
m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS)
Gene: DCPS

Interactor 2: DCPS (Q96C86)
m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS)
Gene: DCPS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 29478914, 32296183, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DcpS~DcpS, DcpS~DcpS_C, DcpS_C~DcpS_C
Common GO terms GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000340 - RNA 7-methylguanosine cap binding
GO:0000932 - P-body
GO:0004532 - RNA exonuclease activity
and 8 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 337
Hs

1 337
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024