HitPredict

Interactor 1: FAF2 (Q96CS3)
FAS-associated factor 2 (UBX domain-containing protein 3B) (UBX domain-containing protein 8)
Gene: FAF2

Interactor 2: AMFR (Q9UKV5)
E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78)
Gene: AMFR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.747

The method score is based on:

Property Details
Experiments 22119785, 18835813, 18775313, 23665563, 26424800, 27387505, 32614325, 21636303
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0030674 - protein-macromolecule adaptor activity
GO:0036503 - ERAD pathway
GO:0043130 - ubiquitin binding
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 445
Hs

1 643
+ Hs
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+ Mm
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+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024