Interactor 1: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Interactor 2: ACE2 (Q9BYF1)
Angiotensin-converting enzyme 2 (EC 3.4.17.23) (Angiotensin-converting enzyme homolog) (ACEH) (Angiotensin-converting enzyme-related carboxypeptidase) (ACE-related carboxypeptidase) (EC 3.4.17.-) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]
Gene: ACE2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 34709727, 33436498
Identification Methods proximity labelling technology, fluorescence polarization spectroscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0030666 - endocytic vesicle membrane
GO:0070062 - extracellular exosome
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 435
Hs

1 805
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024