HitPredict

Interactor 1: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Interactor 2: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 435 Hs			1 2581
+	Hs
		1336314 AP3M1_HUMAN (1-434): 1.4e-123: 366: 24.66		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	At
		96761 AP2M_ARATH (2-435): 8.67e-160: 459: 47.27		CHR5_ARATH (400-1741): 0: 828: 27.14