HitPredict

Interactor 1: GCP3 (Q96CW5)
Gamma-tubulin complex component 3 (GCP-3) (hGCP3) (Gamma-ring complex protein 104 kDa) (h104p) (hGrip104) (Spindle pole body protein Spc98 homolog) (hSpc98)
Gene: TUBGCP3

Interactor 2: GCP5 (Q96RT8)
Gamma-tubulin complex component 5 (GCP-5)
Gene: TUBGCP5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.945

The method score is based on:

Property Details
Experiments 26496610, 28514442, 33961781, 21135143, 23443559, 20360068
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GCP_C_terminal~GCP_C_terminal, GCP_C_terminal~GCP_N_terminal, GCP_N_terminal~GCP_N_terminal
Common GO terms GO:0000278 - mitotic cell cycle
GO:0000923 - equatorial microtubule organizing center
GO:0000930 - gamma-tubulin complex
GO:0005813 - centrosome
GO:0005829 - cytosol
and 6 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 907
Hs

1 1024
+ Hs
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+ Sp
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+ Sp

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Last updated: 15 Jul 2024