HitPredict

Interactor 1: P3C2A (O00443)
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha)
Gene: PIK3C2A

Interactor 2: P3C2A (O00443)
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha)
Gene: PIK3C2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 20562859
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~C2, PI3_PI4_kinase~PI3_PI4_kinase, PI3K_C2~PI3_PI4_kinase, PI3K_rbd~PI3_PI4_kinase, PI3Ka~PI3_PI4_kinase, PI3K_C2~PI3Ka, PI3K_rbd~PI3K_rbd, PI3K_rbd~PI3Ka, PX~PX
Common GO terms GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005802 - trans-Golgi network
GO:0005829 - cytosol
and 27 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1686
Hs

1 1686
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Last updated: 15 Jul 2024