HitPredict

Interactor 1: REPS1 (Q96D71)
RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1)
Gene: REPS1

Interactor 2: BMP2K (Q9NSY1)
BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)
Gene: BMP2K

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 36736316
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 1161
+	Hs
		1244786 REPS2_HUMAN (4-796): 3.9e-87: 291: 32.23		BMP2K_HUMAN (1-1161): 0: 1006: 100.00
+	Hs
		787980 EPS15_HUMAN (4-782): 1.98e-17: 89.3: 10.12		BMP2K_HUMAN (1-1161): 0: 1006: 100.00
+	Hs
		1101671 REPS1_HUMAN (1-796): 2.33e-108: 351: 100.00		AAK1_HUMAN (41-694): 1.99e-122: 402: 49.05
+	Hs
		1101664 REPS2_HUMAN (4-796): 3.9e-87: 291: 32.23		AAK1_HUMAN (41-694): 1.99e-122: 402: 49.05
+	Dm
		91159 E3CTP7_DROME (1-695): 1.93e-74: 260: 11.95		Q7KT38_DROME (39-409): 4.66e-117: 380: 56.02
+	Dm
		112644 M9NDL7_DROME (4-715): 5.2e-57: 212: 21.26		Q7KT38_DROME (39-409): 4.66e-117: 380: 56.02
+	Hs
		270416 ITSN1_HUMAN (1-115): 1.23e-17: 90.4: 16.52		KS6A5_HUMAN (19-708): 1.47e-132: 425: 13.04
+	Sc
		710380 EDE1_YEAST (6-790): 4.29e-60: 223: 16.08		PRK1_YEAST (43-327): 2.35e-49: 191: 37.29
+	Sc
		710372 EDE1_YEAST (6-790): 4.29e-60: 223: 16.08		AKL1_YEAST (43-327): 1.85e-42: 171: 36.39
+	Sc
		692241 PAN1_YEAST (6-778): 8.78e-46: 179: 13.43		ARK1_YEAST (35-336): 1.38e-51: 195: 37.06
+	Sc
		692229 PAN1_YEAST (6-778): 8.78e-46: 179: 13.43		PRK1_YEAST (43-327): 2.35e-49: 191: 37.29
+	Sc
		692220 PAN1_YEAST (6-778): 8.78e-46: 179: 13.43		AKL1_YEAST (43-327): 1.85e-42: 171: 36.39
+	Hs
		161630 EPS15_HUMAN (4-782): 1.98e-17: 89.3: 10.12		GAK_HUMAN (23-313): 2.04e-42: 171: 40.26
+	Hs
		1255607 EHD2_HUMAN (256-370): 1e-40: 159: 33.91		NEK7_HUMAN (53-311): 9.39e-17: 84.3: 27.37
+	Dm
		112588 M9ND00_DROME (1-272): 5.39e-25: 113: 9.23		Q9W3N8_DROME (57-308): 1.88e-15: 83.6: 31.84
+	Dm
		1367922 Q9VIF7_DROME (1-298): 3.21e-23: 108: 10.83		Q9W3N8_DROME (57-308): 1.88e-15: 83.6: 31.84