HitPredict

Interactor 1: SNR40 (Q96DI7)
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57)
Gene: SNRNP40

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 357 Hs			1 779
+	Hs
		903516 WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1331436 NLE1_HUMAN (2-312): 5.34e-81: 256: 21.45		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1309164 TBL1Y_HUMAN (61-357): 1.38e-76: 246: 24.30		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1318178 TBL1R_HUMAN (2-183): 1.23e-48: 172: 24.61		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		793030 LIS1_HUMAN (278-355): 3.21e-19: 90.1: 20.51		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		903302 WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1153371 TBL1R_HUMAN (2-183): 1.23e-48: 172: 24.61		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1146966 A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87		TBD2B_HUMAN (53-512): 3.31e-51: 195: 17.57
+	Mm
		956465 A16L1_MOUSE (41-350): 2.91e-34: 134: 29.56		MPRIP_MOUSE (2-499): 1.35e-47: 184: 16.83
+	Mm
		1149128 A16L1_MOUSE (41-350): 2.91e-34: 134: 29.56		SWP70_MOUSE (55-455): 1.16e-47: 180: 12.35
+	Hs
		1146532 A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		1153322 FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1146500 A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		1146927 A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87		SWP70_HUMAN (55-446): 3.06e-44: 170: 11.36
+	Mm
		1101435 A16L1_MOUSE (41-350): 2.91e-34: 134: 29.56		CYTSA_MOUSE (320-643): 7.93e-41: 164: 12.20
+	Hs
		1167395 FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Mm
		1207691 A16L1_MOUSE (41-350): 2.91e-34: 134: 29.56		TARA_MOUSE (49-500): 9.84e-38: 154: 15.50
+	Hs
		1148943 FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		1240465 POC1A_HUMAN (2-94): 5.27e-17: 83.5: 15.05		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		1146830 A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87		TARA_HUMAN (49-471): 7.83e-20: 97.3: 15.21