HitPredict

Interactor 1: MBD6 (Q96DN6)
Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6)
Gene: MBD6

Interactor 2: ASXL3 (Q9C0F0)
Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3)
Gene: ASXL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36180891
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1003 Hs			1 2248
+	Hs
		1319310 MBD5_HUMAN (1-547): 5.23e-27: 121: 25.57		ASXL3_HUMAN (11-2248): 0: 797: 100.00
+	Hs
		1243841 KMT2C_HUMAN (294-823): 6.65e-14: 78.9: 18.80		ASXL3_HUMAN (11-2248): 0: 797: 100.00
+	Hs
		1176257 MBD6_HUMAN (1-1003): 7.33e-99: 336: 100.00		ASXL2_HUMAN (1196-2248): 2.48e-54: 212: 12.78
+	Hs
		1220800 MBD6_HUMAN (1-1003): 7.33e-99: 336: 100.00		ASXL1_HUMAN (1104-2248): 2.83e-43: 176: 13.52
+	Hs
		554259 MUC1_HUMAN (3-956): 9.92e-59: 222: 13.35		MUC1_HUMAN (48-1095): 1.05e-34: 148: 8.47
+	Hs
		1176274 MBD5_HUMAN (1-547): 5.23e-27: 121: 25.57		ASXL2_HUMAN (1196-2248): 2.48e-54: 212: 12.78
+	Hs
		1220828 MBD5_HUMAN (1-547): 5.23e-27: 121: 25.57		ASXL1_HUMAN (1104-2248): 2.83e-43: 176: 13.52
+	Hs
		1176247 KMT2C_HUMAN (294-823): 6.65e-14: 78.9: 18.80		ASXL2_HUMAN (1196-2248): 2.48e-54: 212: 12.78
+	Hs
		1220790 KMT2C_HUMAN (294-823): 6.65e-14: 78.9: 18.80		ASXL1_HUMAN (1104-2248): 2.83e-43: 176: 13.52
+	Hs
		1056827 MDC1_HUMAN (50-994): 2.38e-25: 116: 10.06		MDC1_HUMAN (402-1995): 1.05e-22: 109: 10.74
+	Dm
		113976 M9PB30_DROME (370-996): 9.47e-23: 108: 11.11		M9PB30_DROME (1371-2237): 8.6e-23: 109: 8.95
+	Hs
		1056876 MDC1_HUMAN (50-994): 2.38e-25: 116: 10.06		MICA3_HUMAN (362-1065): 6.25e-15: 83.5: 15.40
+	Hs
		807793 PRG4_HUMAN (5-598): 6.38e-12: 72: 8.40		MAP1B_HUMAN (48-1352): 3.59e-18: 94.2: 9.02
+	Dm
		54892 Q9VLS7_DROME (31-657): 1.24e-13: 77.8: 11.15		A1ZA72_DROME (315-1139): 2.73e-11: 72: 13.08
+	Dm
		1182373 Q9VLS7_DROME (31-657): 1.24e-13: 77.8: 11.15		Q7KU92_DROME (871-1883): 2.99e-09: 65: 10.60
+	Mm
		1351630 PCLO_MOUSE (11-895): 1.35e-09: 64.7: 10.77		PCLO_MOUSE (1665-2138): 3.25e-10: 68.4: 10.00