HitPredict

Interactor 1: SEH1 (Q96EE3)
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)
Gene: SEH1L

Interactor 2: NELL2 (Q99435)
Protein kinase C-binding protein NELL2 (NEL-like protein 2) (Nel-related protein 2)
Gene: NELL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 360 Hs			1 816
+	Hs
		1240448 POC1A_HUMAN (98-359): 1.13e-51: 178: 13.36		NELL2_HUMAN (1-816): 4.02e-126: 399: 100.00
+	Hs
		1253294 POC1B_HUMAN (202-359): 1.66e-26: 111: 10.70		NELL2_HUMAN (1-816): 4.02e-126: 399: 100.00
+	Hs
		126395 POC1A_HUMAN (98-359): 1.13e-51: 178: 13.36		MATN2_HUMAN (486-795): 1.72e-24: 112: 21.02
+	Hs
		980485 FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34		NOTC2_HUMAN (400-815): 1.5e-25: 116: 19.96
+	Hs
		804311 FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34		NOTC1_HUMAN (167-649): 2.93e-21: 102: 13.36
+	Hs
		944124 FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34		JAG1_HUMAN (158-493): 3.44e-10: 66.1: 8.55
+	Dm
		484996 EBI_DROME (4-146): 2.19e-25: 109: 18.42		CRB_DROME (635-814): 2.66e-10: 66.5: 13.72
+	Hs
		434633 WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52		TSP1_HUMAN (199-741): 5.64e-09: 61.9: 11.05
+	Dm
		484990 CIAO1_DROME (1-146): 1.9e-14: 75.3: 19.64		CRB_DROME (635-814): 2.66e-10: 66.5: 13.72