HitPredict

Interactor 1: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 27312108, 27545878, 29246782, 29311602, 30561431, 29892012, 34755089, 24726323
Identification Methods enzymatic study, affinity chromatography technology, two hybrid, virotrap, two hybrid array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains E3_UbLigase_RBR~E3_UbLigase_RBR, HOIP-UBA~HOIP-UBA, IBR~IBR, PUB~PUB, PUB~PUB_1, PUB_1~PUB_1
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0009898 - cytoplasmic side of plasma membrane
and 17 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1072
Hs

1 1072
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Last updated: 15 Jul 2024