Interactor 1: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31
Interactor 2: SHRPN (Q9H0F6)
Sharpin (Shank-associated RH domain-interacting protein) (Shank-interacting protein-like 1) (hSIPL1)
Gene: SHARPIN
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.770 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26600301, 26670046, 22791023, 28514442, 28978479, 27307491, 27545878, 32019898, 33329596, 33215740, 33961781, 34785643, 34755089, 36276481, 36640323, 24726327, 21455180, 27591049, 28775156, 30561431 and 12 others
more... |
| Identification Methods | affinity chromatography technology, pull down, x-ray crystallography, biochemical, enzymatic study, far western blotting, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, two hybrid, virotrap |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0004842 - ubiquitin-protein transferase activity GO:0005829 - cytosol GO:0042742 - defense response to bacterium GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0043130 - ubiquitin binding and 2 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
