Interactor 1: PLK4 (O00444)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)
Gene: PLK4

Interactor 2: SAS6 (Q6UVJ0)
Spindle assembly abnormal protein 6 homolog (HsSAS-6)
Gene: SASS6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 24613305, 27872092
Identification Methods proximity labelling technology, affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005813 - centrosome
GO:0005814 - centriole
GO:0007099 - centriole replication
GO:0046601 - positive regulation of centriole replication
GO:0098536 - deuterosome
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 970
Hs

1 657
+ Hs
+ Bt
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024