HitPredict

Interactor 1: DC2I2 (Q96EX3)
Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34)
Gene: DYNC2I2

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 536 Hs			1 2517
+	Hs
		1083355 RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		903450 WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		818094 RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Mm
		1141956 RBBP7_MOUSE (105-535): 8.03e-76: 247: 14.38		Q60I23_MOUSE (1102-1308): 2.84e-56: 201: 27.40
+	Hs
		245575 TBL1X_HUMAN (79-424): 4.56e-50: 182: 9.68		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		817868 WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		818441 TBL1R_HUMAN (250-526): 3.44e-47: 173: 12.46		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Mm
		1142008 TBL1R_MOUSE (261-526): 1.88e-47: 174: 13.67		Q60I23_MOUSE (1102-1308): 2.84e-56: 201: 27.40
+	Hs
		1083357 RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16		MINT_HUMAN (730-2515): 3e-28: 127: 9.45
+	Hs
		245570 TBL1X_HUMAN (79-424): 4.56e-50: 182: 9.68		SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28
+	Hs
		1083443 RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		903155 WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65		SRY_HUMAN (1065-1189): 2.77e-37: 142: 25.60
+	Hs
		1033359 DC1I2_HUMAN (42-536): 9.49e-73: 245: 19.69		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		245569 TBL1X_HUMAN (79-424): 4.56e-50: 182: 9.68		SOX5_HUMAN (833-1211): 2.27e-29: 129: 17.71
+	Hs
		1302927 NLE1_HUMAN (10-420): 9.37e-46: 169: 11.16		MINT_HUMAN (730-2515): 3e-28: 127: 9.45
+	Hs
		793042 LIS1_HUMAN (262-536): 4.91e-63: 213: 11.63		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		245652 TBL1X_HUMAN (79-424): 4.56e-50: 182: 9.68		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		1309170 TBL1Y_HUMAN (79-422): 6.5e-49: 178: 9.98		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		903374 WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65		KMT2C_HUMAN (1873-2516): 1.5e-09: 66.4: 10.57
+	Mm
		903669 WDR5_MOUSE (2-341): 1.79e-50: 177: 11.65		KMT2C_MOUSE (641-2516): 2.93e-09: 65.3: 9.74