HitPredict

Interactor 1: DC2I2 (Q96EX3)
Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34)
Gene: DYNC2I2

Interactor 2: DLRB1 (Q9NP97)
Dynein light chain roadblock-type 1 (Bithoraxoid-like protein) (BLP) (Dynein light chain 2A, cytoplasmic) (Dynein-associated protein Km23) (Roadblock domain-containing protein 1)
Gene: DYNLRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27173435, 28718761
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005868 - cytoplasmic dynein complex GO:0005929 - cilium GO:0097542 - ciliary tip
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 96
+	Hs
		1257079 DC2I2_HUMAN (1-536): 4.45e-110: 340: 100.00		DLRB2_HUMAN (1-96): 3.82e-43: 137: 77.08
+	Ce
		219877 O45087_CAEEL (88-534): 2.73e-87: 284: 18.63		Q22752_CAEEL (1-93): 6.46e-34: 113: 49.46
+	Dm
		1096833 DYIN_DROME (67-534): 3.7e-79: 262: 20.91		Q7KMS3_DROME (3-96): 5.78e-41: 131: 74.47
+	Hs
		1033341 DC1I2_HUMAN (42-536): 9.49e-73: 245: 19.69		DLRB1_HUMAN (1-96): 3.9e-43: 137: 100.00
+	Hs
		148111 DC1I1_HUMAN (11-536): 2.11e-70: 239: 18.44		DLRB1_HUMAN (1-96): 3.9e-43: 137: 100.00
+	Hs
		793016 LIS1_HUMAN (262-536): 4.91e-63: 213: 11.63		DLRB2_HUMAN (1-96): 3.82e-43: 137: 77.08
+	Hs
		1257077 DC2I1_HUMAN (63-496): 4.07e-27: 118: 19.05		DLRB2_HUMAN (1-96): 3.82e-43: 137: 77.08
+	Hs
		1261765 DC2I1_HUMAN (63-496): 4.07e-27: 118: 19.05		DLRB1_HUMAN (1-96): 3.9e-43: 137: 100.00