HitPredict

Interactor 1: PLK4 (O00444)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)
Gene: PLK4

Interactor 2: CENPJ (Q9HC77)
Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1)
Gene: CENPJ

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 27872092, 20531387
Identification Methods affinity chromatography technology, protein kinase assay
Interaction Type physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005813 - centrosome
GO:0005814 - centriole
GO:0005829 - cytosol
GO:0007099 - centriole replication
GO:0046601 - positive regulation of centriole replication
and 2 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 970
Hs

1 1338
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024