HitPredict

Interactor 1: MB12A (Q96EY5)
Multivesicular body subunit 12A (CIN85/CD2AP family-binding protein) (ESCRT-I complex subunit MVB12A) (Protein FAM125A)
Gene: MVB12A

Interactor 2: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.698

The method score is based on:

Property Details
Experiments 35271311, 20654576, 24284069, 27609421
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000813 - ESCRT I complex
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0010008 - endosome membrane
GO:0016236 - macroautophagy
and 9 others

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Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 273
Hs

1 390
+ Hs
+ Hs
+ Dm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024