HitPredict

Interactor 1: TRI11 (Q96F44)
E3 ubiquitin-protein ligase TRIM11 (EC 2.3.2.27) (Protein BIA1) (RING finger protein 92) (Tripartite motif-containing protein 11)
Gene: TRIM11

Interactor 2: TRI10 (Q9UDY6)
Tripartite motif-containing protein 10 (B30-RING finger protein) (RING finger protein 9)
Gene: TRIM10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 26186194, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PRY~PRY, PRY~SPRY, SPRY~SPRY, zf-B_box~zf-B_box, zf-B_box~zf-C3HC4
Common GO terms GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination
GO:0045087 - innate immune response
GO:0046597 - negative regulation of viral entry into host cell
and 1 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 468
Hs

1 481
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024