Interactor 1: GFRA2 (O00451)
GDNF family receptor alpha-2 (GDNF receptor alpha-2) (GDNFR-alpha-2) (GFR-alpha-2) (GDNF receptor beta) (GDNFR-beta) (Neurturin receptor alpha) (NRTNR-alpha) (NTNR-alpha) (RET ligand 2) (TGF-beta-related neurotrophic factor receptor 2)
Gene: GFRA2

Interactor 2: NRTN (Q99748)
Neurturin
Gene: NRTN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 9407096, 10829012
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains GDNF~TGF_beta
Common GO terms GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0007399 - nervous system development
GO:0035860 - glial cell-derived neurotrophic factor receptor signaling pathway
GO:1904399 - heparan sulfate binding
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 464
Hs

1 197
+ Hs
+ Hs
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024