Interactor 1: PELI1 (Q96FA3)
E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1) (EC 2.3.2.27) (Pellino-related intracellular-signaling molecule) (RING-type E3 ubiquitin transferase pellino homolog 1)
Gene: PELI1
Interactor 2: IRAK4 (Q9NWZ3)
Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)
Gene: IRAK4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17675297, 28512203, 17997719, 19264966, 21204785, 32296183, 12496252, 16951688, unassigned1304 |
| Identification Methods | affinity chromatography technology, enzymatic study, two hybrid, protein kinase assay, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, phosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0043123 - positive regulation of canonical NF-kappaB signal transduction |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
