Interactor 1: PELI1 (Q96FA3)
E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1) (EC 2.3.2.27) (Pellino-related intracellular-signaling molecule) (RING-type E3 ubiquitin transferase pellino homolog 1)
Gene: PELI1

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 29720226, 12496252, 16951688, 12804775
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0031398 - positive regulation of protein ubiquitination
GO:0034450 - ubiquitin-ubiquitin ligase activity
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 418
Hs

1 522
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024