HitPredict

Interactor 1: DYL2 (Q96FJ2)
Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2)
Gene: DYNLL2

Interactor 2: PZRN3 (Q9UPQ7)
E3 ubiquitin-protein ligase PDZRN3 (EC 2.3.2.27) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (RING-type E3 ubiquitin transferase PDZRN3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)
Gene: PDZRN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 1066
+	Hs
		928525 DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26		PZRN3_HUMAN (1-1066): 0: 665: 100.00
+	Hs
		928313 DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26		DLG2_HUMAN (212-975): 9.35e-64: 235: 12.17
+	Hs
		1077286 DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00		DLG2_HUMAN (212-975): 9.35e-64: 235: 12.17
+	Hs
		928467 DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26		RNF41_HUMAN (1-200): 9.95e-54: 192: 32.85
+	Hs
		1291294 DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00		RNF41_HUMAN (1-200): 9.95e-54: 192: 32.85
+	Hs
		928259 DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26		DLG4_HUMAN (239-345): 1.97e-16: 86.6: 34.58
+	Mm
		928550 DYL1_MOUSE (1-89): 1.8e-47: 147: 93.26		DLG4_MOUSE (239-343): 1.76e-16: 86.6: 35.24
+	Rn
		928570 DYL1_RAT (1-89): 1.8e-47: 147: 93.26		DLG3_RAT (111-450): 2.65e-16: 86.2: 15.12
+	Hs
		942366 DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00		DLG4_HUMAN (239-345): 1.97e-16: 86.6: 34.58