HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: K1C14 (P02533)
Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)
Gene: KRT14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Hs			1 472
+	Hs
		129174 P85B_HUMAN (1-728): 0: 549: 100.00		K1C16_HUMAN (1-441): 3.53e-146: 427: 84.42
+	Hs
		129281 P85B_HUMAN (1-728): 0: 549: 100.00		K1C17_HUMAN (108-470): 1.08e-144: 422: 82.37
+	Hs
		129196 P85B_HUMAN (1-728): 0: 549: 100.00		K1C15_HUMAN (114-468): 8.15e-137: 403: 68.82
+	Hs
		129187 P85B_HUMAN (1-728): 0: 549: 100.00		K1C10_HUMAN (110-420): 1.2e-131: 394: 69.43
+	Hs
		129223 P85B_HUMAN (1-728): 0: 549: 100.00		K1C20_HUMAN (100-463): 5.83e-122: 364: 55.22
+	Hs
		129304 P85B_HUMAN (1-728): 0: 549: 100.00		K2C79_HUMAN (21-444): 5.3e-86: 275: 26.40
+	Hs
		129243 P85B_HUMAN (1-728): 0: 549: 100.00		K2C6C_HUMAN (23-445): 1.16e-75: 249: 25.18
+	Hs
		129188 P85B_HUMAN (1-728): 0: 549: 100.00		K2C5_HUMAN (80-429): 1.41e-74: 247: 26.99
+	Hs
		129148 P85B_HUMAN (1-728): 0: 549: 100.00		KRT38_HUMAN (18-434): 1.75e-73: 240: 43.17
+	Mm
		403444 SRC_MOUSE (535-728): 1.19e-28: 122: 18.81		K1C14_MOUSE (1-472): 1.09e-153: 447: 85.48
+	Hs
		337481 ABL1_HUMAN (532-725): 2.04e-30: 130: 21.54		K1H1_HUMAN (75-441): 4.71e-138: 405: 53.93
+	Hs
		442835 HCK_HUMAN (551-724): 1.01e-30: 128: 22.53		K1H1_HUMAN (75-441): 4.71e-138: 405: 53.93
+	Mm
		403471 SRC_MOUSE (535-728): 1.19e-28: 122: 18.81		K1C16_MOUSE (1-423): 3.07e-136: 402: 78.64
+	Hs
		522739 SRC_HUMAN (535-728): 1.04e-28: 123: 18.81		K1C10_HUMAN (110-420): 1.2e-131: 394: 69.43
+	Hs
		280510 HCK_HUMAN (551-724): 1.01e-30: 128: 22.53		KRT34_HUMAN (108-426): 1.34e-121: 362: 58.31
+	Hs
		280771 HCK_HUMAN (551-724): 1.01e-30: 128: 22.53		KRT36_HUMAN (2-470): 1.07e-80: 259: 49.59
+	Hs
		442865 HCK_HUMAN (551-724): 1.01e-30: 128: 22.53		KRT35_HUMAN (2-434): 1.15e-79: 256: 51.04
+	Hs
		213936 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		KRT86_HUMAN (7-434): 1.14e-97: 304: 24.71
+	Hs
		531557 BTK_HUMAN (551-727): 5.38e-31: 131: 20.65		K2C5_HUMAN (80-429): 1.41e-74: 247: 26.99
+	Mm
		403456 SRC_MOUSE (535-728): 1.19e-28: 122: 18.81		K2C5_MOUSE (80-429): 2.63e-73: 243: 26.99