Interactor 1: TRM61 (Q96FX7)
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC 2.1.1.220) (mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A) (EC 2.1.1.-) (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A)
Gene: TRMT61A

Interactor 2: TRM6 (Q9UJA5)
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6)
Gene: TRMT6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 33961781, 26186194, 28514442, 16043508
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GCD14~Gcd10p
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030488 - tRNA methylation
GO:0031515 - tRNA (m1A) methyltransferase complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 289
Hs

1 497
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024