HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Hs			1 646
+	Hs
		129217 P85B_HUMAN (1-728): 0: 549: 100.00		HS71L_HUMAN (2-646): 0: 966: 82.48
+	Hs
		129192 P85B_HUMAN (1-728): 0: 549: 100.00		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		503732 VAV2_HUMAN (561-717): 1.41e-31: 134: 21.18		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		503608 ABL2_HUMAN (545-725): 5.17e-31: 132: 25.28		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		411965 FYN_HUMAN (556-721): 1.61e-31: 131: 20.69		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		337324 ABL1_HUMAN (532-725): 2.04e-30: 130: 21.54		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		411570 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		433227 YES_HUMAN (556-728): 9.82e-31: 129: 19.34		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		442767 HCK_HUMAN (551-724): 1.01e-30: 128: 22.53		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		503340 SRC_HUMAN (535-728): 1.04e-28: 123: 18.81		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		411586 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		442775 HCK_HUMAN (551-724): 1.01e-30: 128: 22.53		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		503720 BMX_HUMAN (541-726): 1.9e-24: 110: 19.69		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		503596 CSK_HUMAN (324-446): 1.13e-24: 109: 26.02		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		789047 ABL2_HUMAN (545-725): 5.17e-31: 132: 25.28		HSP72_HUMAN (2-646): 0: 940: 85.47
+	Hs
		503489 P85A_HUMAN (606-721): 5.69e-21: 100: 28.81		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		564025 CSK_HUMAN (324-446): 1.13e-24: 109: 26.02		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		503853 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		713938 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		HS71L_HUMAN (2-646): 0: 966: 82.48
+	Hs
		503950 PTN11_HUMAN (622-723): 5.34e-12: 71: 24.56		HSP7C_HUMAN (1-646): 0: 967: 100.00