HitPredict

Interactor 1: WBP1 (Q96G27)
WW domain-binding protein 1 (WBP-1)
Gene: WBP1

Interactor 2: WWP1 (Q9H0M0)
NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
Gene: WWP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.50	0.632

Property	Details
Experiments	26186194, 28514442, 9169421, 33961781
Identification Methods	affinity chromatography technology, unspecified method, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 269 Hs			1 922
+	Hs
		1291858 WBP1_HUMAN (1-269): 2.82e-160: 447: 100.00		ITCH_HUMAN (1-922): 0: 884: 57.14
+	Hs
		125643 WBP1_HUMAN (1-269): 2.82e-160: 447: 100.00		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		1291859 WBP1_HUMAN (1-269): 2.82e-160: 447: 100.00		NED4L_HUMAN (1-919): 0: 822: 33.16
+	Mm
		1206454 WBP1L_MOUSE (22-230): 2.32e-95: 285: 38.24		WWP1_MOUSE (1-922): 0: 942: 90.02
+	Hs
		808224 WBP1_HUMAN (1-269): 2.82e-160: 447: 100.00		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Mm
		1206455 WBP1L_MOUSE (22-230): 2.32e-95: 285: 38.24		ITCH_MOUSE (1-922): 0: 862: 57.54
+	Mm
		1206456 WBP1L_MOUSE (22-230): 2.32e-95: 285: 38.24		WWP2_MOUSE (1-922): 0: 841: 57.30
+	Mm
		93278 WBP1L_MOUSE (22-230): 2.32e-95: 285: 38.24		E9PXB7_MOUSE (129-919): 0: 696: 34.71
+	Mm
		808346 WBP1_MOUSE (1-269): 3.03e-142: 403: 74.67		NEDD4_MOUSE (3-446): 4.73e-51: 195: 18.83
+	Hs
		1291869 WBP1_HUMAN (1-269): 2.82e-160: 447: 100.00		HECW2_HUMAN (141-582): 1.9e-12: 73.8: 16.11