HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 526
+	Hs
		337375 ABL1_HUMAN (532-725): 2.04e-30: 130: 21.54		FUS_HUMAN (1-526): 1.99e-39: 152: 100.00
+	Hs
		967124 BTK_HUMAN (551-727): 5.38e-31: 131: 20.65		EWS_HUMAN (3-451): 5.13e-31: 129: 31.05
+	Hs
		337433 ABL1_HUMAN (532-725): 2.04e-30: 130: 21.54		EWS_HUMAN (3-451): 5.13e-31: 129: 31.05
+	Hs
		726729 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		FUS_HUMAN (1-526): 1.99e-39: 152: 100.00
+	Hs
		788962 MATK_HUMAN (558-722): 1.29e-13: 76: 21.84		EWS_HUMAN (3-451): 5.13e-31: 129: 31.05
+	Hs
		522960 SRC_HUMAN (535-728): 1.04e-28: 123: 18.81		PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00
+	Hs
		516342 SRC_HUMAN (535-728): 1.04e-28: 123: 18.81		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44
+	Hs
		523147 SRC_HUMAN (535-728): 1.04e-28: 123: 18.81		PABP3_HUMAN (275-379): 5.23e-10: 63.9: 19.05
+	Dm
		90745 M9PAY7_DROME (320-471): 8.07e-14: 72.5: 24.84		E1JI93_DROME (59-284): 4.71e-13: 74.3: 17.70
+	Hs
		516450 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44