HitPredict

Interactor 1: RN185 (Q96GF1)
E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)
Gene: RNF185

Interactor 2: SRPRB (Q9Y5M8)
Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1)
Gene: SRPRB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	32738194, 32614325, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 271
+	Hs
		1307275 RNF5_HUMAN (15-173): 2.18e-37: 129: 60.38		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Hs
		1356617 AMFR_HUMAN (27-171): 2.12e-24: 101: 19.18		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Zm
		9970 A0A1D6F168_MAIZE (3-92): 1.67e-24: 100: 25.28		A0A1D6GEU6_MAIZE (46-240): 2.09e-64: 202: 22.56
+	Hs
		1292356 RN185_HUMAN (1-192): 2.35e-56: 178: 100.00		SAR1A_HUMAN (62-195): 1.47e-11: 64: 24.63