HitPredict

Interactor 1: DCNL1 (Q96GG9)
DCN1-like protein 1 (DCNL1) (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene)
Gene: DCUN1D1

Interactor 2: KLH13 (Q9P2N7)
Kelch-like protein 13 (BTB and kelch domain-containing protein 2)
Gene: KLHL13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0097602 - cullin family protein binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 259 Hs			1 655
+	Hs
		1292398 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLHL9_HUMAN (43-655): 0: 548: 92.82
+	Hs
		1121255 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH22_HUMAN (38-651): 1.39e-136: 415: 32.54
+	Hs
		1292374 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH15_HUMAN (63-638): 1.97e-100: 320: 32.27
+	Hs
		1292397 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLHL8_HUMAN (441-653): 6.63e-49: 182: 28.04
+	Hs
		1292409 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH20_HUMAN (472-652): 2.43e-39: 155: 24.73
+	Hs
		299530 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH18_HUMAN (469-648): 2.17e-38: 151: 23.08
+	Hs
		299519 DCNL2_HUMAN (1-257): 3.46e-130: 370: 78.21		KLH18_HUMAN (469-648): 2.17e-38: 151: 23.08
+	Hs
		1161488 DCNL2_HUMAN (1-257): 3.46e-130: 370: 78.21		KLH24_HUMAN (426-650): 1.38e-27: 119: 20.26
+	Hs
		1121487 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH26_HUMAN (420-651): 4.86e-20: 96.5: 15.94
+	Hs
		1120800 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH12_HUMAN (522-650): 3e-19: 93.8: 24.24