HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:1903076 - regulation of protein localization to plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Hs			1 2364
+	Hs
		411676 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Hs
		433700 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Hs
		211480 SRC_HUMAN (535-728): 1.04e-28: 123: 18.81		ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58
+	Hs
		360640 BTK_HUMAN (551-727): 5.38e-31: 131: 20.65		SPTA1_HUMAN (179-1394): 3.14e-92: 337: 19.60
+	Hs
		337296 ABL1_HUMAN (532-725): 2.04e-30: 130: 21.54		SPTA1_HUMAN (179-1394): 3.14e-92: 337: 19.60
+	Hs
		521527 BTK_HUMAN (551-727): 5.38e-31: 131: 20.65		ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25
+	Hs
		521454 SRC_HUMAN (535-728): 1.04e-28: 123: 18.81		ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25
+	Hs
		297808 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		411682 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		433710 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		433543 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		DMD_HUMAN (234-2093): 2.37e-21: 105: 9.67
+	Hs
		337470 ABL1_HUMAN (532-725): 2.04e-30: 130: 21.54		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		411715 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		411637 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		433753 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		433640 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		411889 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		MACF1_HUMAN (687-1920): 4.98e-16: 87.6: 12.23
+	Hs
		434078 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		MACF1_HUMAN (687-1920): 4.98e-16: 87.6: 12.23
+	Hs
		164551 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10
+	Hs
		164555 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10