HitPredict

Interactor 1: MYO19 (Q96H55)
Unconventional myosin-XIX (Myosin head domain-containing protein 1)
Gene: MYO19

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007015 - actin filament organization GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 970 Hs			1 817
+	Hs
		1293073 MYO19_HUMAN (1-970): 0: 1069: 100.00		NEB1_HUMAN (1-817): 2.29e-110: 364: 46.47
+	Rn
		192528 MYO5A_RAT (10-965): 0: 1024: 28.53		NEB2_RAT (1-817): 2.3e-118: 379: 95.23
+	Mm
		1164029 MYO5A_MOUSE (10-965): 0: 1023: 28.63		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		724975 MYH9_HUMAN (9-907): 0: 997: 28.63		NEB2_HUMAN (1-817): 3.09e-122: 389: 100.00
+	Rn
		192523 MYO5B_RAT (26-964): 0: 998: 28.82		NEB2_RAT (1-817): 2.3e-118: 379: 95.23
+	Rn
		192527 MYH10_RAT (2-965): 0: 997: 26.24		NEB2_RAT (1-817): 2.3e-118: 379: 95.23
+	Mm
		1143165 MYH10_MOUSE (2-965): 0: 1000: 26.14		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		93873 E9QPE7_MOUSE (2-965): 0: 998: 26.24		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		1132056 MYH4_MOUSE (2-928): 0: 997: 26.67		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		1164008 MYH9_MOUSE (9-965): 0: 992: 26.84		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		1293034 MYO19_HUMAN (1-970): 0: 1069: 100.00		ERBIN_HUMAN (11-583): 1.56e-42: 170: 13.02
+	Hs
		1200034 MYO5A_HUMAN (10-937): 0: 1027: 29.21		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Hs
		725194 MYH10_HUMAN (2-965): 0: 998: 26.14		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Hs
		724903 MYH9_HUMAN (9-907): 0: 997: 28.63		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Hs
		724926 MYH9_HUMAN (9-907): 0: 997: 28.63		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Ce
		136791 HUM6_CAEEL (13-923): 0: 993: 29.44		UNC89_CAEEL (2-312): 5.97e-20: 98.3: 14.29
+	Mm
		1164123 V9GX76_MOUSE (50-677): 8.81e-119: 395: 36.01		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		1356907 MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01		NEB1_HUMAN (1-817): 2.29e-110: 364: 46.47
+	Hs
		1300694 MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01		MAGI1_HUMAN (462-688): 1.9e-10: 66.9: 10.48